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Humans are among the least fertile of any species on earth. 
Pregnancy is a result of a complex combination of factors and events. 
 
According to statistics, infertility affects about 12 to 15 percent of the reproductive-age population, irrespective of their age group. 
In infertile couples, both men and women account for 40% of infertility cases each and 20% of infertility cases are due to a joint problem. Surveys suggest that as many as 50% of ‘trying to conceive’ couples lifestyles have not left them in the best condition for conception. 
So the average time to conceive can vary greatly and is a concern to those who are having difficulty to get pregnant. 
When pregnancy does not happen straight away, couples may experience a creeping anxiety. 



The babystart® FertilMate™ Scrotum Cooling Patch is a specially designed hydrogel pad with natural l-menthol used to provide the cooling effect. 

The Cooling Patch has a pleasant aroma and a slim, flexible, non-messy format. It is easily trimmed and shaped for use on all sizes of scrotum and comes in a re-sealable bag, with no need for refrigeration.

There are two versions of the FertilMate™ Scrotum Cooling Patch, a 'Trial' pack of 8 off patches for those men that want to ensure that the patch can be worn successfully by them, either one a day whilst at work or during daytime 'warm' periods and/or another one worn during sleep. Then there is a full boxed set which contains 32 off patches for an effective use of one spermatogenesis cycle, 16 days at 2 patches per day, one worn whilst at work or during daytime 'warm' periods and the other during sleep.

  • Cooling: the FertilMate™ Patch helps maintain an optimal temperature beneficial to spermatogenesis.
  • Soothing: natural, relaxing, long-lasting cooling right where you need it.
  • Effective: FertilMate™ will immediately feel cool or slightly 'tingy' and this effect will last for 2-4 hours, while the soothing effect will last much longer. After 6-8 hours we recommend that the patch is replaced with a fresh one.
  • Beneficial: testicular temperature highly correlates with scrotal temperature and "increased intrascrotal temperature is prevalent in subfertile men regardless of clinical diagnosis". (A.W. Zorgniotti and A.I. Sealfon: J. Reprod. Fert. (1988) 82,563-566)
  • Recommended Use: testicular temperature is affected by numerous issues, some of which are medical problems and some of which are man made. Driving or sitting for hours at work increases testicular temperature, as does sleeping and particularly if you sleep on your side. 
  • FertilMate™ helps reduce testicular temperature in these 'warm' working and 'warm' sleeping periods.
  • Spermatogenesis: sperm development is called spermatogenesis. Each spermatogenesis cycle has about six stages. The duration of each cycle is about 16 days. Five cycles are required to produce one mature sperm. Therefore, it takes approximately 86 days for a complete spermatogenetic cycle. Because the process is so complex, any illness or prolonged raised testicular temperature events during the first cycle could affect sperm formation and these events tend to affect ALL the sperm, not just one or two.
  • Frequency of use: the FertilMate™ Cooling Patch should ideally be used for six months, although initial improvements in sperm quality may be seen after three months. At the very least, one full 'initial cycle' of 16 days should be tried and that is why each full boxed set of FertilMate™ contains 16 pouches (two patches per pouch), as we recommend the wearing of one patch during working hours and one during sleeping hours

A relationship between experimental elevation of testis temperature and poor semen quality has been known for over eighty years. 
Experience shows that prolonged reduction of the temperature of the scrotal area by about 2 to 5 degrees C., may be effective in reversing male infertility and  there are numerous published study data to support this theory, a selection of which are here;

Mulcahy JJ, J Urol 1984: 132:469-70
Abstract: Fifty men with reduced sperm motility were tested with scrotal cooling by ice packs applied to the scrotum at night and held in place with jockey shorts. Sperm density and motility were compared before and after treatment. At least a 2-fold increase in sperm density and comparable increases in sperm motility were seen in 65 per cent of the patients in this series. The percentage of successful treatment was the same whether or not a varicocele was present. These results further support the detrimental influence of heat on spermatogenesis

J. Reprod. Fert. (1988) 82, 563-566
Measurement of intrascrotal temperature in normal and subfertile men.
Summary: Scrotal temperatures were measured in 300 sub fertile men (mean sperm count 21.4 million/ml) and 30 control men (mean sperm count 118.7 million/ml). The sub fertile men had mean temperatures of 34.75 degrees C for the testes. The value for the testes of the control men was 
33.4 degrees C. 
The difference 1.35 degrees C was significant (P= 0.03). An intrascrotal temperature above 34.1 degrees C was found in 83% of the sub fertile men, regardless of clinical diagnosis. We suggest that small intrinsic temperature increases may interfere with the ability of the testis to accommodate to environmental temperature stresses and so lead to abnormal semen and sub fertility.

European Journal of Obstetrics & Gynecology & Reproductive Biology, 29 (1988) 137-141. Influence of occupation and living habits on semen quality in men (scrotal insulation and semen quality)
Abstract: 56 Infertile couples were split into two different groups and their semen quality examined. Patients in which there was no evidence or interference with normal testicular thermo regulation either during the day or the night were classified as ‘cool workers’ and ‘cool sleepers’ In the other Group, ‘warm workers’ and ‘warm sleepers’, there was evidence for scrotal insulation. The number of good moving spermatozoa per ejaculate as well as the number per ml was greater in ‘cool workers/sleepers’ than in ‘warm workers/sleepers’. 

Human Reproduction vol. 15 no.6 pp.1355-1357, 2000
Increase in scrotal temperature in car drivers.
Scrotal temperature increases while driving a car. This study demonstrated that driving is associated with an increase in scrotal temperature. 
Such an increase reaches a value of 1.7 to 2.2 degrees C when driving continuously for more than 2 hours. The question arises as to what the consequences of an increase in scrotal temperature on sperm characteristics and or fertility might be. Normal human testicular temperature is physiologically maintained within a range 32 -35 degrees C (Mieusset and Bujan, 1995). As in most mammals, such a normal testis temperature is a necessary condition for quantitatively and qualitatively normal spermatogenesis (Setchell and Mieusset, 1996). In human experimental studies in which a 1-2 degree increase in testis temperature was induced at least during waking hours and repeated daily, spermatogenesis was impaired: sperm count and percentages of motile and of normal form spermatozoa were depressed (Mieusset et al., 1985, 1987; Shafik, 1992; Mieusset and Bujan, 1994).

2005: Jung A; Schill W-B; Schuppe H-C
Improvement of semen quality by nocturnal scrotal cooling in oligozoospermic men with a history of testicular maldescent.
International journal of andrology 2005;28(2):93-8
.
The aim of this study was to evaluate the influence of nocturnal scrotal cooling on semen quality in such patients presenting with oligozoospermia. Twenty infertile men with a history of testicular maldescent and oligozoospermia were included for nocturnal scrotal cooling over 12 weeks for every night. Semen analysis was performed at the beginning of the cooling period and at weeks 4, 8 and 12. Another 20 infertile patients with a history of testicular maldescent and oligozoospermia were followed without specific treatment and served as a retrospectively built control group. Scrotal cooling at night resulted in a scrotal temperature drop by 0.8 degrees C (median). A significant increase in sperm concentration and total sperm count was achieved by nocturnal cooling after 8 weeks and 12 weeks respectively. The improvement of sperm motility and sperm morphology was statistically insignificant. This study suggests nocturnal scrotal cooling as a therapeutic option.
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